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tecovirimat will boost the level or outcome of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Watch. Tecovirimat is often a weak inhibitor of CYP2C8 and CYP2C19. Keep an eye on for adverse outcomes if coadministered with delicate substrates of such enzymes.butabarbital will minimize the level or effect of diazepam by affecting